PPIAP78

Across TCGA pan-cancer cohorts, PPIAP78 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PPIAP78 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PPIAP78 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP78 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

ACC, HNSC, and UCS are the cancer types where PPIAP78 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.324	0.775	.001	53	view →
HNSC	OS	Median	All	0.438	0.255	<.001	52	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
BRCA	OS	Quartile	IV	0.218	0.796	<.001	33	view →
SKCM	OS	Median	III,IV	0.856	0.736	.010	30	view →
LGG	OS	Median	All	0.367	0.556	.001	27	view →
KICH	OS	Median	II,III,IV	0.667	0.927	.017	23	view →
LIHC	OS	Median	All	0.454	0.642	.002	21	view →
UVM	DFS	Quartile	All	0.456	0.804	.019	19	view →
LUAD	DFS	Quartile	All	0.786	0.554	.002	18	view →
STAD	DFS	Median	III,IV	0.291	0.563	.023	14	view →
THCA	DFS	Median	All	0.966	0.903	.001	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PPIAP78–ACC (OS)

Open the ACC breakdown →