PPIAP49

Across TCGA patient cohorts, PPIAP49 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,476 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP49-associated GO terms across cancer lineages are Mitochondrial cytochrome c oxidase assembly, Mitochondrial translation, and Proteasome assembly. Each is linked with PPIAP49 in more than 16 cancer types. Because this analysis shows association rather than direction, both PPIAP49-to-partner and partner-to-PPIAP49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial cytochrome c oxidase assembly grouped by PPIAP49-low versus PPIAP49-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP49→partner) and Y-score (partner→PPIAP49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.030	+0.141	<.001	<.001	3	16
STAD	Mitochondrial translation →	+0.048	+0.234	<.001	<.001	3	16
STAD	Proteasome assembly →	+0.049	+0.246	<.001	<.001	3	15
ESCA	Outer mitochondrial membrane organization →	+0.059	+0.300	.006	<.001	1	17
STAD	Protein insertion into membrane →	+0.040	+0.175	<.001	<.001	3	15
STAD	Respiratory chain complex IV assembly →	+0.031	+0.153	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,476 associations by consensus.

Mitochondrial cytochrome c oxidase assembly by PPIAP49 expression — STAD

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