PPIAP14

Across TCGA patient cohorts, PPIAP14 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,543 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PPIAP14-associated GO terms across cancer lineages are Ribosome assembly, Mitochondrial respiratory chain complex assembly, and Ribosomal large subunit assembly. Each is linked with PPIAP14 in more than 18 cancer types. Because this analysis shows association rather than direction, both PPIAP14-to-partner and partner-to-PPIAP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome assembly grouped by PPIAP14-low versus PPIAP14-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP14→partner) and Y-score (partner→PPIAP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Ribosome assembly →	+0.046	+0.276	<.001	<.001	3	18
STAD	Mitochondrial respiratory chain complex assembly →	+0.055	+0.392	<.001	<.001	2	19
ESCA	Ribosomal large subunit assembly →	+0.047	+0.252	<.001	<.001	3	16
ESCA	Regulation of protein ubiquitination →	+0.069	+0.378	.005	<.001	2	17
STAD	Establishment of protein localization to mitochondrial membrane →	+0.046	+0.266	.001	<.001	3	15
STAD	RNA 5'-end processing →	+0.032	+0.237	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,543 associations by consensus.

Ribosome assembly by PPIAP14 expression — ESCA

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