PPIAP14

Across TCGA pan-cancer cohorts, PPIAP14 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PPIAP14’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PPIAP14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAP14 is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.

KIRC, BRCA, and LUSC are the cancer types where PPIAP14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPIAP14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	+0.225	<.001	11	view →
BRCA	All	All	−0.317	<.001	6	view →
LUSC	All	All	+0.558	<.001	4	view →
LIHC	Female	All	+0.100	.001	4	view →
HNSC	Female	All	−0.258	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PPIAP14–KIRC

Open the KIRC breakdown →