PPIAL4G

Across TCGA cell cohorts, PPIAL4G RNA expression is significantly associated with the go_rna of many other GO terms, with 915 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPIAL4G-associated GO terms across cancer lineages are Spindle assembly, Cell division, and Double-strand break repair via nonhomologous end joining. Each is linked with PPIAL4G in more than 4 cancer types. Because this analysis shows association rather than direction, both PPIAL4G-to-partner and partner-to-PPIAL4G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle assembly grouped by PPIAL4G-low versus PPIAL4G-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4G→partner) and Y-score (partner→PPIAL4G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Spindle assembly →	+0.046	+0.007	.008	.008	3	5
LARGE_INTESTINE	Cell division →	+0.065	+0.009	<.001	.002	3	5
LUNG_NSCLC_LUAD	Double-strand break repair via nonhomologous end joining →	+0.043	+0.008	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Regulation of G1/S transition of mitotic cell cycle →	+0.067	+0.008	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.084	+0.010	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Regulation of double-strand break repair →	+0.069	+0.009	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 915 associations by consensus.

Spindle assembly by PPIAL4G expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →