Q-omics provides the consensus-scored PPATP1 profile across patient tissues and cancer cell-line models. PPATP1 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, PPATP1 is differentially expressed in 10, with the highest sampling consensus in COAD. Additionally, PPATP1 RNA expression shows 6,488 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, COAD, and STAD as cancer lineages where PPATP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPATP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPATP1 survival associations across molecular data types. PPATP1 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPATP1 RNA expression–survival associations across cancer types. High PPATP1 expression shows unfavorable associations in MESO, KICH, LGG, DLBC and PAAD, but favorable associations in HNSC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for PPATP1 RNA expression.
This table summarizes PPATP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for PPATP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPATP1 shows higher tumor expression in COAD, BRCA, HNSC, KIRP, LUAD and UCEC. The COAD box plot shows higher PPATP1 RNA expression in tumor versus normal tissue (log2 FC = +0.085, t-test p < 0.001).
This table shows molecular features associated with PPATP1 in patient tissues and cancer cell lines. In patient samples, PPATP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
