PPATP1

Across TCGA patient cohorts, PPATP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,488 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPATP1-associated GO terms across cancer lineages are XMP metabolic process, Regulation of microtubule-based process, and Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with PPATP1 in more than 21 cancer types. Because this analysis shows association rather than direction, both PPATP1-to-partner and partner-to-PPATP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XMP metabolic process grouped by PPATP1-low versus PPATP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPATP1→partner) and Y-score (partner→PPATP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	XMP metabolic process →	+0.071	+0.163	<.001	<.001	3	22
STAD	Regulation of microtubule-based process →	+0.043	+0.158	<.001	<.001	3	19
STAD	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.070	+0.163	<.001	<.001	3	19
ESCA	Postreplication repair →	+0.062	+0.203	<.001	<.001	3	19
ESCA	Obsolete mRNA methylation →	+0.051	+0.135	<.001	<.001	3	19
STAD	Purine nucleobase biosynthetic process →	+0.061	+0.146	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,488 associations by consensus.

XMP metabolic process by PPATP1 expression — STAD

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