PPARD

Across TCGA patient cohorts, PPARD protein abundance is significantly associated with the RNA expression of many other genes, with 2,019 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PPARD-associated genes across cancer lineages are GOSR2, CXCL5, and SP2-AS1. Each is linked with PPARD in more than 1 cancer types. Because this analysis shows association rather than direction, both PPARD-to-partner and partner-to-PPARD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPARD versus GOSR2 in HNSC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPARD→partner) and Y-score (partner→PPARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GOSR2 →	-0.671	-0.974	.001	<.001	3	2
HNSC	CXCL5 →	+2.250	+0.980	<.001	<.001	3	2
HNSC	SP2-AS1 →	-0.679	-0.582	.008	.005	3	2
HNSC	AQP9 →	+2.114	+0.856	<.001	<.001	3	2
HNSC	IL1B →	+2.161	+0.835	<.001	<.001	3	2
LUAD	TREML4 →	+0.768	+0.782	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,019 associations by consensus.

PPARD vs GOSR2 — HNSC

Explore this scatter interactively →