PPAN-P2RY11

Across TCGA patient cohorts, PPAN-P2RY11 mutation is significantly associated with the RNA expression of many other genes, with 2,416 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPAN-P2RY11-associated genes across cancer lineages are SERBP1P4, SLC25A51P3, and LINC01072. Each is linked with PPAN-P2RY11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPAN-P2RY11-to-partner and partner-to-PPAN-P2RY11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERBP1P4 grouped by PPAN-P2RY11-low versus PPAN-P2RY11-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPAN-P2RY11→partner) and Y-score (partner→PPAN-P2RY11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SERBP1P4 →	+0.034	+5.812	.001	.003	3	2
LIHC	SLC25A51P3 →	+0.064	+4.355	<.001	.001	3	2
LIHC	LINC01072 →	+0.091	+4.305	<.001	.007	3	2
BLCA	SNX18P5 →	+0.045	+4.497	.001	.009	3	2
OV	OR10G7 →	+0.037	+6.036	<.001	.002	3	2
OV	RNU5A-5P →	+0.713	+4.991	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,416 associations by consensus.

SERBP1P4 by PPAN-P2RY11 expression — CESC

Explore this box plot interactively →