PPAN-P2RY11

Across TCGA pan-cancer cohorts, PPAN-P2RY11 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PPAN-P2RY11 data layer compared with 3 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher PPAN-P2RY11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPAN-P2RY11 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

UCS, ACC, and KIRP are the cancer types where PPAN-P2RY11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	III,IV	0.236	0.715	.001	92	view →
ACC	DFS	Median	All	0.390	0.732	<.001	69	view →
KIRP	DFS	Quartile	All	0.828	0.954	.008	32	view →
KIRC	DFS	Median	II,III,IV	0.790	0.551	.004	28	view →
PAAD	DFS	Median	II,III,IV	0.494	0.295	.009	20	view →
LUSC	DFS	Quartile	III,IV	0.351	0.993	.018	14	view →
LIHC	DFS	Median	All	0.564	0.338	.007	14	view →
HNSC	DFS	Median	All	0.242	0.452	.011	13	view →
GBM	DFS	Quartile	All	0.207	0.481	.003	12	view →
UVM	OS	Median	III,IV	0.836	0.258	.007	12	view →
LAML	DFS	Quartile	All	0.211	0.510	.039	10	view →
SCLC	DFS	Quartile	III,IV	0.219	0.516	.030	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PPAN-P2RY11–UCS (OS)

Open the UCS breakdown →