PPAN-P2RY11

Across TCGA cell cohorts, PPAN-P2RY11 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPAN-P2RY11-associated genes across cancer lineages are GALR3, CPLX4, and PROKR1. Each is linked with PPAN-P2RY11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPAN-P2RY11-to-partner and partner-to-PPAN-P2RY11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALR3 grouped by PPAN-P2RY11-low versus PPAN-P2RY11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPAN-P2RY11→partner) and Y-score (partner→PPAN-P2RY11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GALR3 →	+0.088	+3.424	.004	.006	3	1
LARGE_INTESTINE	CPLX4 →	+0.020	+3.807	.003	.001	3	1
LARGE_INTESTINE	PROKR1 →	+0.045	+4.047	<.001	.001	3	1
LARGE_INTESTINE	DBX2 →	+0.009	+3.240	<.001	.004	3	1
LARGE_INTESTINE	F11 →	+0.042	+2.882	<.001	.005	3	1
LARGE_INTESTINE	SH3GL2 →	+1.565	+3.252	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GALR3 by PPAN-P2RY11 expression — LARGE_INTESTINE

Explore this box plot interactively →