POU5F1P5

Across TCGA patient cohorts, POU5F1P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,714 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POU5F1P5-associated GO terms across cancer lineages are Regulation of mRNA processing, Regulation of cell projection assembly, and Positive regulation of protein catabolic process. Each is linked with POU5F1P5 in more than 18 cancer types. Because this analysis shows association rather than direction, both POU5F1P5-to-partner and partner-to-POU5F1P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by POU5F1P5-low versus POU5F1P5-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU5F1P5→partner) and Y-score (partner→POU5F1P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of mRNA processing →	+0.069	+0.389	<.001	<.001	3	19
STAD	Regulation of cell projection assembly →	+0.050	+0.357	<.001	<.001	3	19
STAD	Positive regulation of protein catabolic process →	+0.047	+0.348	<.001	<.001	3	18
STAD	Regulation of mRNA splicing, via spliceosome →	+0.059	+0.377	<.001	<.001	3	18
ESCA	Membrane fusion →	+0.053	+0.473	.001	<.001	3	18
STAD	Negative regulation of DNA-templated transcription, elongation →	+0.051	+0.263	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,714 associations by consensus.

Regulation of mRNA processing by POU5F1P5 expression — ESCA

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