POU5F1P5

Across TCGA pan-cancer cohorts, POU5F1P5 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated POU5F1P5 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher POU5F1P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated POU5F1P5 expression acts as an unfavorable survival marker, although some lineages such as THCA show a favorable association.

BRCA, ACC, and KICH are the cancer types where POU5F1P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	III,IV	0.846	0.924	.002	68	view →
ACC	OS	Tertile	All	0.604	0.839	<.001	57	view →
KICH	DFS	Tertile	III,IV	0.051	0.816	<.001	36	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	18	view →
KIRP	DFS	Tertile	III,IV	0.465	0.720	.046	9	view →
PAAD	OS	Tertile	II,III,IV	0.476	0.627	.027	7	view →
ESCA	OS	Tertile	IV	0.243	0.738	.024	6	view →
READ	DFS	Quartile	IV	0.300	0.643	.012	6	view →
OV	OS	Quartile	IV	0.590	0.934	.028	4	view →
LUSC	DFS	Median	II,III,IV	0.237	0.448	.023	4	view →
KIRC	DFS	Quartile	IV	0.184	0.369	.029	3	view →
THCA	DFS	Tertile	II,III,IV	0.971	0.883	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

POU5F1P5–BRCA (OS)

Open the BRCA breakdown →