Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, POU5F1B mutation is significantly associated with the RNA expression of many other genes, with 1,450 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible POU5F1B-associated genes across cancer lineages are RORA-AS2, RDXP2, and RNU4-81P. Each is linked with POU5F1B in more than 1 cancer types. Because this analysis shows association rather than direction, both POU5F1B-to-partner and partner-to-POU5F1B results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (POU5F1B→partner) and Y-score (partner→POU5F1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.