Q-omics provides the consensus-scored NDUFA5P3 profile across patient tissues and cancer cell-line models. NDUFA5P3 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, NDUFA5P3 is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, NDUFA5P3 RNA expression shows 6,475 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, HNSC, and STAD as cancer lineages where NDUFA5P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NDUFA5P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NDUFA5P3 survival associations across molecular data types. NDUFA5P3 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NDUFA5P3 RNA expression–survival associations across cancer types. High NDUFA5P3 expression shows unfavorable associations in SKCM, THCA, UCEC, READ and OV, but favorable associations in MESO. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for NDUFA5P3 RNA expression.
This table summarizes NDUFA5P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for NDUFA5P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NDUFA5P3 shows lower tumor expression in KICH and higher tumor expression in HNSC, PRAD and LIHC. The HNSC box plot shows higher NDUFA5P3 RNA expression in tumor versus normal tissue (log2 FC = +0.064, t-test p = .032).
This table shows molecular features associated with NDUFA5P3 in patient tissues and cancer cell lines. In patient samples, NDUFA5P3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
