POP4

Across TCGA cell cohorts, POP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,401 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible POP4-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Positive regulation of cell cycle phase transition, and Positive regulation of chromosome condensation. Each is linked with POP4 in more than 10 cancer types. Because this analysis shows association rather than direction, both POP4-to-partner and partner-to-POP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by POP4-low versus POP4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POP4→partner) and Y-score (partner→POP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.093	+0.600	<.001	<.001	3	11
STOMACH	Positive regulation of cell cycle phase transition →	+0.079	+0.597	.002	.003	3	11
CNS	Positive regulation of chromosome condensation →	+0.121	+0.621	<.001	.003	3	10
BREAST	Mitotic spindle assembly checkpoint signaling →	+0.119	+0.778	.002	.005	2	11
BREAST	Spindle assembly checkpoint signaling →	+0.119	+0.778	.002	.005	2	11
BREAST	Mitotic spindle checkpoint signaling →	+0.119	+0.778	.002	.005	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

DNA replication-dependent chromatin assembly by POP4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →