POM121L7P

Across TCGA patient cohorts, POM121L7P mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POM121L7P-associated genes across cancer lineages are EDDM3B, DPPA3P2, and MIR580. Each is linked with POM121L7P in more than 1 cancer types. Because this analysis shows association rather than direction, both POM121L7P-to-partner and partner-to-POM121L7P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EDDM3B grouped by POM121L7P-low versus POM121L7P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121L7P→partner) and Y-score (partner→POM121L7P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EDDM3B →	+0.492	+3.786	<.001	.002	3	1
UCEC	DPPA3P2 →	+0.118	+2.995	<.001	.005	3	1
UCEC	MIR580 →	+0.434	+3.562	<.001	.004	3	1
UCEC	MIR181B1 →	+0.360	+3.344	<.001	.007	3	1
UCEC	TRAJ31 →	+0.906	+3.235	.002	.003	3	1
UCEC	TCP11X2 →	+0.168	+2.916	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

EDDM3B by POM121L7P expression — UCEC

Explore this box plot interactively →