Across TCGA pan-cancer cohorts, POM121L7P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of POM121L7P’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where POM121L7P RNA is repressed in tumor relative to normal tissue. In most cancer types POM121L7P is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
PAAD and COAD are the cancer types where POM121L7P tumor–normal differential expression is most reproducible.