POM121L4P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, POM121L4P Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated POM121L4P data layer compared with 18 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher POM121L4P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated POM121L4P expression acts as an unfavorable survival marker.

UCEC, ESCA, and COAD are the cancer types where POM121L4P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIV0.2310.592.0366view →
ESCADFSMedianAll0.0980.533.0036view →
COADDFSMedianAll0.4640.785.0302view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration