Across TCGA pan-cancer cohorts, POM121L4P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of POM121L4P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where POM121L4P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types POM121L4P is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

HNSC, BRCA, and LIHC are the cancer types where POM121L4P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POM121L4P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	+0.060	.025	4	view →
BRCA	All	All	−0.027	.028	4	view →
LIHC	All	II,III,IV	+0.020	.018	4	view →
LUAD	Male	All	−0.065	.023	2	view →
KIRC	Male	II,III,IV	−0.035	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: POM121L4P RNA expression & survival · all POM121L4P data types