Across TCGA patient cohorts, POM121L4P mutation is significantly associated with the RNA expression of many other genes, with 296 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POM121L4P-associated genes across cancer lineages are EIF4E, RAD17, and HEATR3. Each is linked with POM121L4P in more than 1 cancer types. Because this analysis shows association rather than direction, both POM121L4P-to-partner and partner-to-POM121L4P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121L4P→partner) and Y-score (partner→POM121L4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF4E →	+0.694	+3.375	<.001	.005	3	1
UCEC	RAD17 →	+0.545	+3.227	.008	.009	3	1
UCEC	HEATR3 →	+0.723	+3.332	<.001	.005	3	1
UCEC	MIER3 →	+0.709	+3.332	.004	.005	3	1
UCEC	LZIC →	+0.724	+3.332	.003	.005	3	1
UCEC	DNAJB4 →	+1.058	+3.343	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 296 associations by consensus.

Exploration

POM121L4P survival (RNA) · tumor vs normal (RNA) · all POM121L4P data types