POM121L3P

Across TCGA pan-cancer cohorts, POM121L3P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated POM121L3P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher POM121L3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated POM121L3P expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

KICH, ACC, and ESCA are the cancer types where POM121L3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.057	0.917	<.001	108	view →
ACC	OS	Tertile	III,IV	0.189	0.764	.004	48	view →
ESCA	OS	Tertile	IV	0.743	0.290	.013	30	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	30	view →
HNSC	OS	Tertile	III,IV	0.775	0.605	.022	21	view →
KIRP	OS	Tertile	III,IV	1.000	0.327	.030	12	view →
THCA	OS	Tertile	All	0.935	0.980	.002	12	view →
GBM	OS	Tertile	All	0.194	0.428	.033	9	view →
THYM	DFS	Tertile	II,III,IV	0.542	0.878	.040	9	view →
LGG	DFS	Tertile	All	0.754	0.843	.049	6	view →
LUSC	OS	Tertile	All	0.666	0.825	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

POM121L3P–KICH (DFS)

Open the KICH breakdown →