Across TCGA patient cohorts, POM121B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,947 significant associations in total. OV shows the largest number of these associations.

The most reproducible POM121B-associated GO terms across cancer lineages are Negative regulation of protein sumoylation, Positive regulation of isotype switching to IgA isotypes, and Negative regulation of telomere capping. Each is linked with POM121B in more than 30 cancer types. Because this analysis shows association rather than direction, both POM121B-to-partner and partner-to-POM121B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121B→partner) and Y-score (partner→POM121B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	Negative regulation of protein sumoylation →	+0.131	+0.468	<.001	<.001	3	31
DLBC	Positive regulation of isotype switching to IgA isotypes →	+0.092	+0.653	<.001	<.001	3	31
DLBC	Negative regulation of telomere capping →	+0.066	+0.619	<.001	<.001	3	30
OV	Obsolete regulation of histone methylation →	+0.057	+0.458	<.001	<.001	3	29
DLBC	Regulation of cytokinesis →	+0.054	+0.570	<.001	<.001	3	29
UCS	Establishment of mitotic sister chromatid cohesion →	+0.104	+0.537	<.001	.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,947 associations by consensus.

Exploration

POM121B survival (RNA) · tumor vs normal (RNA) · all POM121B data types