Across TCGA pan-cancer cohorts, POM121B RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated POM121B data layer.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher POM121B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated POM121B expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.
STAD, BRCA, and UVM are the cancer types where POM121B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.