POLR3GL

Across TCGA patient cohorts, POLR3GL RNA expression is significantly associated with the protein abundance of many other proteins, with 14,802 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible POLR3GL-associated proteins across cancer lineages are LARP4_S722, SEPTIN2, and RPS6. Each is linked with POLR3GL in more than 5 cancer types. Because this analysis shows association rather than direction, both POLR3GL-to-partner and partner-to-POLR3GL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3GL versus LARP4_S722 in LUAD, with a Pearson correlation of -0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3GL→partner) and Y-score (partner→POLR3GL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LARP4_S722 →	-0.460	-0.364	<.001	<.001	3	6
BRCA	SEPTIN2 →	+0.312	+0.486	<.001	<.001	3	5
GBM	RPS6 →	-0.463	-0.258	.002	.001	3	5
BRCA	DDX21_S121 →	-0.645	-0.353	<.001	<.001	3	5
PDAC	FNDC3B →	-0.433	-0.366	<.001	<.001	3	5
LUAD	UTP11 →	-0.367	-0.354	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,802 associations by consensus.

POLR3GL vs LARP4_S722 — LUAD

Explore this scatter interactively →