POLR3GL

Across TCGA patient cohorts, POLR3GL protein abundance is significantly associated with the RNA expression of many other genes, with 6,497 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POLR3GL-associated genes across cancer lineages are SFI1, DAPP1, and JAK3. Each is linked with POLR3GL in more than 2 cancer types. Because this analysis shows association rather than direction, both POLR3GL-to-partner and partner-to-POLR3GL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3GL versus SFI1 in HNSC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3GL→partner) and Y-score (partner→POLR3GL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SFI1 →	+0.613	+0.576	.008	.002	3	3
COAD	DAPP1 →	-1.352	-0.817	.002	.008	3	3
OV	JAK3 →	-1.076	-0.610	.001	.001	3	3
COAD	TNFRSF13C →	-1.058	-0.835	.001	.006	3	3
COAD	IKZF3 →	-1.139	-0.714	.001	<.001	3	3
HNSC	C15orf40 →	+0.552	+0.486	.005	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,497 associations by consensus.

POLR3GL vs SFI1 — HNSC

Explore this scatter interactively →