POLR3G

Across TCGA patient cohorts, POLR3G protein abundance is significantly associated with the RNA expression of many other genes, with 11,845 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POLR3G-associated genes across cancer lineages are SYTL4, TNS2, and TTK. Each is linked with POLR3G in more than 2 cancer types. Because this analysis shows association rather than direction, both POLR3G-to-partner and partner-to-POLR3G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3G versus SYTL4 in BRCA, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3G→partner) and Y-score (partner→POLR3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYTL4 →	-1.071	-0.812	<.001	.001	3	3
BRCA	TNS2 →	-0.901	-0.789	<.001	<.001	3	3
UCEC	TTK →	+1.821	+1.233	<.001	.001	3	3
UCEC	ZNF670-ZNF695 →	+0.935	+0.971	.001	.003	3	3
UCEC	CCDC150 →	+1.192	+1.051	<.001	<.001	3	3
LSCC	SKA1 →	+1.053	+0.575	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,845 associations by consensus.

POLR3G vs SYTL4 — BRCA

Explore this scatter interactively →