POLR3G

Across TCGA cell cohorts, POLR3G RNA expression is significantly associated with the go_rna of many other GO terms, with 4,755 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible POLR3G-associated GO terms across cancer lineages are DNA-templated transcription termination, GMP biosynthetic process, and IMP biosynthetic process. Each is linked with POLR3G in more than 18 cancer types. Because this analysis shows association rather than direction, both POLR3G-to-partner and partner-to-POLR3G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription termination grouped by POLR3G-low versus POLR3G-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3G→partner) and Y-score (partner→POLR3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription termination →	+0.134	+1.679	<.001	<.001	3	19
OVARY	GMP biosynthetic process →	+0.161	+1.748	<.001	<.001	3	17
URINARY_TRACT	IMP biosynthetic process →	+0.180	+1.604	<.001	<.001	3	17
BONE	rRNA processing →	+0.152	+1.674	<.001	<.001	3	17
PANCREAS	Maturation of SSU-rRNA →	+0.131	+1.641	<.001	<.001	3	17
BONE	Ribosome biogenesis →	+0.142	+1.307	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,755 associations by consensus.

DNA-templated transcription termination by POLR3G expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →