POLR3D

Across TCGA patient cohorts, POLR3D RNA expression is significantly associated with the protein abundance of many other proteins, with 13,006 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POLR3D-associated proteins across cancer lineages are CCAR2, XPO7, and PPP2R2A. Each is linked with POLR3D in more than 9 cancer types. Because this analysis shows association rather than direction, both POLR3D-to-partner and partner-to-POLR3D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3D versus CCAR2 in OV, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3D→partner) and Y-score (partner→POLR3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCAR2 →	+0.424	+0.690	<.001	<.001	3	10
OV	XPO7 →	+0.353	+0.499	<.001	<.001	3	9
OV	PPP2R2A →	+0.645	+0.825	<.001	<.001	3	7
OV	R3HCC1 →	+0.379	+0.592	.004	.001	3	6
BRCA	PBK →	+0.601	+0.453	<.001	<.001	3	6
OV	CHMP7 →	+0.363	+0.812	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,006 associations by consensus.

POLR3D vs CCAR2 — OV

Explore this scatter interactively →