POLR2LP1

Across TCGA patient cohorts, POLR2LP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,732 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible POLR2LP1-associated GO terms across cancer lineages are Cell-cell junction organization, Biological process involved in interaction with host, and Positive regulation of peptidase activity. Each is linked with POLR2LP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both POLR2LP1-to-partner and partner-to-POLR2LP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-cell junction organization grouped by POLR2LP1-low versus POLR2LP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2LP1→partner) and Y-score (partner→POLR2LP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cell-cell junction organization →	+0.037	+0.135	<.001	<.001	3	12
STAD	Biological process involved in interaction with host →	+0.044	+0.250	<.001	<.001	3	12
STAD	Positive regulation of peptidase activity →	+0.036	+0.205	<.001	<.001	3	11
STAD	Non-canonical NF-kappaB signal transduction →	+0.033	+0.189	<.001	<.001	3	11
OV	Regulation of sphingolipid biosynthetic process →	+0.032	+0.086	<.001	.002	3	11
STAD	Regulation of lamellipodium organization →	+0.033	+0.186	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,732 associations by consensus.

Cell-cell junction organization by POLR2LP1 expression — STAD

Explore this box plot interactively →