POLR2J

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POLR2J protein abundance is significantly associated with the protein abundance of many other proteins, with 3,572 significant associations in total. COAD shows the largest number of these associations.

The most reproducible POLR2J-associated proteins across cancer lineages are PCNT_S1653, CALU, and CCDC137_S19. Each is linked with POLR2J in more than 1 cancer types. Because this analysis shows association rather than direction, both POLR2J-to-partner and partner-to-POLR2J results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR2J versus PCNT_S1653 in COAD, with a Pearson correlation of -0.65.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2J→partner) and Y-score (partner→POLR2J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPCNT_S1653 →-0.521-1.539<.001.00132
COADCALU →-0.528-1.122<.001<.00132
COADCCDC137_S19 →+0.907+1.731.003<.00132
OVEEF2_T57 →+1.429+0.872<.001<.00132
COADEIF3D →+0.354+1.956<.001<.00132
COADHCFC1 →+0.240+1.420.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,572 associations by consensus.

POLR2J vs PCNT_S1653 — COAD

Per-sample scatter of POLR2J vs PCNT_S1653 in COAD (Pearson r = -0.65).

Explore this scatter interactively →

Exploration