POLR2H

Across TCGA patient cohorts, POLR2H RNA expression is significantly associated with the protein abundance of many other proteins, with 15,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR2H-associated proteins across cancer lineages are FXR1, EIF4G1, and GMPS. Each is linked with POLR2H in more than 8 cancer types. Because this analysis shows association rather than direction, both POLR2H-to-partner and partner-to-POLR2H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR2H versus FXR1 in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2H→partner) and Y-score (partner→POLR2H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FXR1 →	+0.568	+0.981	<.001	<.001	3	9
LSCC	EIF4G1 →	+0.397	+1.030	<.001	<.001	3	8
LSCC	GMPS →	+0.524	+0.767	<.001	<.001	3	8
LSCC	RFC4 →	+0.548	+0.936	<.001	<.001	3	8
LUAD	CDK1 →	+0.740	+0.431	<.001	<.001	3	7
LSCC	CSE1L →	+0.329	+0.706	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,848 associations by consensus.

POLR2H vs FXR1 — LSCC

Explore this scatter interactively →