POLR2H

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POLR2H protein abundance is significantly associated with the RNA expression of many other genes, with 16,708 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR2H-associated genes across cancer lineages are KIF14, NCAPG2, and RFC4. Each is linked with POLR2H in more than 7 cancer types. Because this analysis shows association rather than direction, both POLR2H-to-partner and partner-to-POLR2H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR2H versus KIF14 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2H→partner) and Y-score (partner→POLR2H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKIF14 →+1.252+0.307<.001<.00138
GBMNCAPG2 →+0.696+0.210<.001.00138
OVRFC4 →+0.992+0.358<.001.00138
HNSCFAM136A →+0.626+0.216<.001<.00138
LSCCTRIP13 →+1.076+0.439<.001<.00138
UCECAURKA →+1.517+0.327<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,708 associations by consensus.

POLR2H vs KIF14 — UCEC

Per-sample scatter of POLR2H vs KIF14 in UCEC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration