Across TCGA patient cohorts, POLR1D RNA expression is significantly associated with the protein abundance of many other proteins, with 13,355 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR1D-associated proteins across cancer lineages are ZMYM2, GTF2F2, and GTF2F1. Each is linked with POLR1D in more than 7 cancer types. Because this analysis shows association rather than direction, both POLR1D-to-partner and partner-to-POLR1D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1D→partner) and Y-score (partner→POLR1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZMYM2 →	+0.343	+0.418	<.001	<.001	3	8
GBM	GTF2F2 →	+0.395	+0.295	<.001	<.001	3	8
BRCA	GTF2F1 →	+0.300	+0.451	<.001	<.001	3	7
COAD	HMGB1 →	+0.429	+0.483	<.001	<.001	3	7
LSCC	POLR1D_S104 →	+0.488	+0.550	<.001	<.001	3	7
CCRCC	NUDT15 →	+0.414	+0.348	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,355 associations by consensus.

Exploration

POLR1D survival (RNA) · tumor vs normal (RNA) · all POLR1D data types