Across TCGA patient cohorts, POLR1D mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLR1D-associated genes across cancer lineages are HSC and lymphatic Endothelial cells. Each is linked with POLR1D in more than 1 cancer types. Because this analysis shows association rather than direction, both POLR1D-to-partner and partner-to-POLR1D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1D→partner) and Y-score (partner→POLR1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSC →	+0.140	+2.815	.020	.036	2	1
UCEC	lymphatic Endothelial cells →	-0.026	-3.116	.048	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

POLR1D survival (RNA) · tumor vs normal (RNA) · all POLR1D data types