Across TCGA cell cohorts, POLR1D RNA expression is significantly associated with the go_rna of many other GO terms, with 3,601 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible POLR1D-associated GO terms across cancer lineages are Positive regulation of actin filament bundle assembly, Positive regulation of stress fiber assembly, and Protein activation cascade. Each is linked with POLR1D in more than 11 cancer types. Because this analysis shows association rather than direction, both POLR1D-to-partner and partner-to-POLR1D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1D→partner) and Y-score (partner→POLR1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of actin filament bundle assembly →	-0.144	-0.506	.006	.002	3	12
LUNG_NSCLC_LUSC	Positive regulation of stress fiber assembly →	-0.131	-1.138	<.001	.002	3	11
LUNG_NSCLC_LUSC	Protein activation cascade →	-0.320	-0.858	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction organization →	-0.126	-0.459	.002	.009	2	11
BONE	Regulation of actin filament bundle assembly →	-0.095	-0.563	.007	.002	3	10
CNS	Collagen biosynthetic process →	-0.229	-0.889	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,601 associations by consensus.

Exploration

POLR1D survival (RNA) · tumor vs normal (RNA) · all POLR1D data types