POLN

Across TCGA patient cohorts, POLN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,494 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POLN-associated proteins across cancer lineages are QDPR, RAI14, and RPS2. Each is linked with POLN in more than 2 cancer types. Because this analysis shows association rather than direction, both POLN-to-partner and partner-to-POLN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLN versus QDPR in BRCA, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLN→partner) and Y-score (partner→POLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	QDPR →	+0.557	+0.389	<.001	<.001	3	3
PDAC	RAI14 →	+0.257	+0.091	<.001	.003	3	3
HNSC	RPS2 →	-0.197	-0.254	<.001	.002	3	3
OV	ARL1 →	-0.292	-0.314	<.001	.004	3	3
GBM	MYO1E →	-0.509	-0.373	<.001	<.001	3	3
HNSC	NECTIN4 →	-0.468	-0.276	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,494 associations by consensus.

POLN vs QDPR — BRCA

Explore this scatter interactively →