POLDIP2

Across TCGA patient cohorts, POLDIP2 protein abundance is significantly associated with the protein abundance of many other proteins, with 28,877 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLDIP2-associated proteins across cancer lineages are DAP3, DNAJA3, and DNAJC19. Each is linked with POLDIP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both POLDIP2-to-partner and partner-to-POLDIP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLDIP2 versus DAP3 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLDIP2→partner) and Y-score (partner→POLDIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DAP3 →	+0.515	+0.378	<.001	<.001	3	10
LUAD	DNAJA3 →	+0.392	+0.252	<.001	<.001	3	10
LSCC	DNAJC19 →	+0.552	+0.379	<.001	<.001	3	10
LSCC	FASTKD2 →	+0.544	+0.406	<.001	<.001	3	10
COAD	PMPCA →	+0.399	+0.247	<.001	<.001	3	10
OV	PMPCB →	+0.458	+0.333	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,877 associations by consensus.

POLDIP2 vs DAP3 — LSCC

Explore this scatter interactively →