PODN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PODN protein abundance is significantly associated with the RNA expression of many other genes, with 15,728 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PODN-associated genes across cancer lineages are MGP, LMOD1, and LINC00702. Each is linked with PODN in more than 9 cancer types. Because this analysis shows association rather than direction, both PODN-to-partner and partner-to-PODN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PODN versus MGP in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PODN→partner) and Y-score (partner→PODN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMGP →+1.637+0.549<.001.002310
UCECLMOD1 →+1.560+0.602<.001<.001310
HNSCLINC00702 →+0.999+0.415<.001<.001310
OVSRPX →+1.321+0.425<.001<.00139
UCECRASL12 →+0.912+0.625<.001<.00139
UCECSFRP4 →+2.383+0.632<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,728 associations by consensus.

PODN vs MGP — BRCA

Per-sample scatter of PODN vs MGP in BRCA (Pearson r = 0.31).

Explore this scatter interactively →

Exploration