POC1B-GALNT4

Across TCGA patient cohorts, POC1B-GALNT4 mutation is significantly associated with the RNA expression of many other genes, with 1,290 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POC1B-GALNT4-associated genes across cancer lineages are FAM219B, LRRC57, and RNA5SP273. Each is linked with POC1B-GALNT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both POC1B-GALNT4-to-partner and partner-to-POC1B-GALNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM219B grouped by POC1B-GALNT4-low versus POC1B-GALNT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POC1B-GALNT4→partner) and Y-score (partner→POC1B-GALNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM219B →	+0.491	+2.906	<.001	.001	3	2
UCEC	LRRC57 →	+0.405	+2.732	.001	.002	3	2
UCEC	RNA5SP273 →	+0.419	+2.494	<.001	.002	3	2
UCEC	RNA5SP176 →	+0.321	+3.437	<.001	.002	3	2
SKCM	RNU6-895P →	+0.214	+3.292	<.001	.006	3	2
SKCM	RNU6-172P →	+0.324	+3.715	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,290 associations by consensus.

FAM219B by POC1B-GALNT4 expression — UCEC

Explore this box plot interactively →