POC1B-GALNT4

Across TCGA pan-cancer cohorts, POC1B-GALNT4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated POC1B-GALNT4 data layer compared with 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher POC1B-GALNT4 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated POC1B-GALNT4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, UCEC, and THCA are the cancer types where POC1B-GALNT4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.406	0.245	.002	96	view →
UCEC	OS	Tertile	All	0.766	0.573	<.001	96	view →
THCA	DFS	Quartile	III,IV	0.513	0.925	.001	55	view →
KIRC	DFS	Median	All	0.755	0.498	<.001	53	view →
BRCA	OS	Tertile	III,IV	0.961	0.846	.002	43	view →
LGG	DFS	Median	All	0.669	0.797	<.001	34	view →
UCS	OS	Median	IV	0.817	0.302	.002	24	view →
LIHC	DFS	Quartile	All	0.439	0.583	.009	16	view →
ACC	DFS	Quartile	All	0.468	0.786	.007	15	view →
READ	OS	Tertile	All	1.000	0.333	.003	14	view →
LUAD	OS	Median	II,III,IV	0.628	0.363	.019	13	view →
STAD	OS	Tertile	IV	0.744	0.348	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

POC1B-GALNT4–HNSC (DFS)

Open the HNSC breakdown →