PNMA8B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PNMA8B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,570 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PNMA8B-associated GO terms across cancer lineages are Vesicle targeting, rough ER to cis-Golgi, Regulation of transcription initiation by RNA polymerase II, and Cytoplasmic translation. Each is linked with PNMA8B in more than 5 cancer types. Because this analysis shows association rather than direction, both PNMA8B-to-partner and partner-to-PNMA8B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA8B→partner) and Y-score (partner→PNMA8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCVesicle targeting, rough ER to cis-Golgi →+0.112+1.020<.001<.00136
LUNG_SCLCRegulation of transcription initiation by RNA polymerase II →+0.063+0.592<.001.00236
SOFT_TISSUECytoplasmic translation →+0.059+0.353<.001.00235
LUNG_NSCLC_LUSCCellular respiration →+0.091+0.110<.001.00835
CNSRegulation of systemic arterial blood pressure by hormone →-0.120-0.230.003<.00135
SOFT_TISSUEMitochondrial electron transport, cytochrome c to oxygen →+0.064+0.226<.001.00535
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,570 associations by consensus.

Exploration