PMS2P11

Across TCGA patient cohorts, PMS2P11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,543 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PMS2P11-associated GO terms across cancer lineages are Canonical NF-kappaB signal transduction, Phospholipid biosynthetic process, and Positive regulation of canonical NF-kappaB signal transduction. Each is linked with PMS2P11 in more than 11 cancer types. Because this analysis shows association rather than direction, both PMS2P11-to-partner and partner-to-PMS2P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Canonical NF-kappaB signal transduction grouped by PMS2P11-low versus PMS2P11-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMS2P11→partner) and Y-score (partner→PMS2P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Canonical NF-kappaB signal transduction →	+0.046	+0.164	.004	<.001	3	12
STAD	Phospholipid biosynthetic process →	+0.031	+0.104	<.001	<.001	3	12
ESCA	Positive regulation of canonical NF-kappaB signal transduction →	+0.065	+0.216	.004	<.001	3	12
ESCA	Positive regulation of DNA recombination →	+0.050	+0.168	.008	<.001	3	12
STAD	Positive regulation of post-translational protein modification →	+0.029	+0.098	<.001	<.001	3	12
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.028	+0.091	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,543 associations by consensus.

Canonical NF-kappaB signal transduction by PMS2P11 expression — ESCA

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