PMS2P11

Across TCGA pan-cancer cohorts, PMS2P11 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated PMS2P11 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PMS2P11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PMS2P11 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

KIRP, LUSC, and SKCM are the cancer types where PMS2P11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.734	0.886	.008	30	view →
LUSC	OS	Tertile	III,IV	0.565	0.308	.012	25	view →
SKCM	DFS	Tertile	III,IV	0.403	0.679	.017	24	view →
LGG	DFS	Tertile	All	0.256	0.409	<.001	24	view →
STAD	DFS	Tertile	IV	0.095	0.565	.003	21	view →
PAAD	OS	Tertile	II,III,IV	0.414	0.651	.031	18	view →
LUAD	DFS	Tertile	IV	0.322	0.725	.034	18	view →
CESC	OS	Tertile	IV	0.225	0.632	.022	18	view →
ACC	OS	Tertile	III,IV	0.189	0.757	<.001	18	view →
UCEC	DFS	Tertile	IV	0.194	0.726	<.001	18	view →
BLCA	OS	Tertile	III,IV	0.718	0.526	.045	9	view →
SARC	DFS	Tertile	All	0.288	0.609	.006	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

PMS2P11–KIRP (DFS)

Open the KIRP breakdown →