PMPCB

Across TCGA patient cohorts, PMPCB RNA expression is significantly associated with the protein abundance of many other proteins, with 14,865 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PMPCB-associated proteins across cancer lineages are GTF2I, PUS7, and MEPCE. Each is linked with PMPCB in more than 8 cancer types. Because this analysis shows association rather than direction, both PMPCB-to-partner and partner-to-PMPCB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMPCB versus GTF2I in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMPCB→partner) and Y-score (partner→PMPCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTF2I →	+0.447	+0.575	<.001	.001	3	9
LSCC	PUS7 →	+0.538	+0.610	<.001	<.001	3	8
LSCC	MEPCE →	+0.429	+0.588	<.001	<.001	3	7
OV	BUD23 →	+0.457	+0.460	<.001	<.001	3	6
LSCC	ORC5 →	+0.378	+0.493	<.001	<.001	3	6
OV	CDK5 →	+0.434	+0.372	.003	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,865 associations by consensus.

PMPCB vs GTF2I — HNSC

Explore this scatter interactively →