PMPCB

Across TCGA patient cohorts, PMPCB protein abundance is significantly associated with the RNA expression of many other genes, with 16,353 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PMPCB-associated genes across cancer lineages are CNRIP1, GYPC, and FLI1. Each is linked with PMPCB in more than 6 cancer types. Because this analysis shows association rather than direction, both PMPCB-to-partner and partner-to-PMPCB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMPCB versus CNRIP1 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMPCB→partner) and Y-score (partner→PMPCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CNRIP1 →	-0.913	-0.383	<.001	<.001	3	7
GBM	GYPC →	-0.790	-0.285	.001	.001	3	7
BRCA	FLI1 →	-0.583	-0.241	<.001	<.001	3	7
OV	ANTXR2 →	-0.817	-0.326	<.001	.001	3	7
OV	CALHM5 →	-0.729	-0.291	<.001	.004	3	7
OV	LHFPL6 →	-1.144	-0.345	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,353 associations by consensus.

PMPCB vs CNRIP1 — UCEC

Explore this scatter interactively →