PMFBP1

Across TCGA patient cohorts, PMFBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 775 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PMFBP1-associated genes across cancer lineages are MAGED2, C22orf31, and CA2. Each is linked with PMFBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PMFBP1-to-partner and partner-to-PMFBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMFBP1 versus MAGED2 in BRCA, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMFBP1→partner) and Y-score (partner→PMFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MAGED2 →	-0.876	-0.544	.001	.001	3	2
HNSC	C22orf31 →	-0.484	-0.579	.002	<.001	3	1
HNSC	CA2 →	+1.676	+0.669	.001	.007	3	1
HNSC	EBI3 →	-0.940	-0.651	<.001	<.001	3	1
HNSC	PLGLB2 →	-0.418	-0.596	.007	.009	3	1
HNSC	VPREB3 →	-0.657	-0.566	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 775 associations by consensus.

PMFBP1 vs MAGED2 — BRCA

Explore this scatter interactively →