PMF1-BGLAP

Across TCGA patient cohorts, PMF1-BGLAP RNA expression is significantly associated with the go_rna of many other GO terms, with 7,157 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PMF1-BGLAP-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, [2Fe-2S] cluster assembly, and Response to interleukin-3. Each is linked with PMF1-BGLAP in more than 23 cancer types. Because this analysis shows association rather than direction, both PMF1-BGLAP-to-partner and partner-to-PMF1-BGLAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by PMF1-BGLAP-low versus PMF1-BGLAP-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PMF1-BGLAP→partner) and Y-score (partner→PMF1-BGLAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.107	+1.118	<.001	<.001	3	24
ESCA	[2Fe-2S] cluster assembly →	+0.044	+0.381	<.001	<.001	3	20
THYM	Response to interleukin-3 →	-0.072	-0.532	<.001	<.001	3	18
MESO	Interleukin-5-mediated signaling pathway →	-0.095	-0.536	<.001	.002	1	20
CHOL	Dendritic cell antigen processing and presentation →	-0.093	-0.663	<.001	.002	2	18
DLBC	Alanine transport →	-0.067	-1.113	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,157 associations by consensus.

[4Fe-4S] cluster assembly by PMF1-BGLAP expression — DLBC

Explore this box plot interactively →