PMF1-BGLAP

Across TCGA pan-cancer cohorts, PMF1-BGLAP RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PMF1-BGLAP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PMF1-BGLAP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PMF1-BGLAP expression acts as an unfavorable survival marker, although some lineages such as PAAD and THCA show a favorable association.

KIRC, LIHC, and COAD are the cancer types where PMF1-BGLAP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.825	0.916	<.001	71	view →
LIHC	OS	Median	All	0.589	0.769	<.001	66	view →
COAD	DFS	Quartile	All	0.733	0.893	<.001	58	view →
BLCA	OS	Median	All	0.560	0.792	.002	57	view →
ACC	DFS	Tertile	All	0.157	0.617	<.001	45	view →
KICH	DFS	Median	All	0.685	1.000	.006	38	view →
PAAD	OS	Median	All	0.540	0.250	<.001	33	view →
THCA	DFS	Tertile	All	0.909	0.711	.001	29	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.296	.013	21	view →
UVM	DFS	Quartile	III,IV	1.000	0.439	.018	17	view →
UCS	DFS	Tertile	IV	0.488	0.942	.024	12	view →
SCLC	DFS	Median	All	0.676	0.441	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PMF1-BGLAP–KIRC (DFS)

Open the KIRC breakdown →