PMF1-BGLAP

Across TCGA pan-cancer cohorts, PMF1-BGLAP RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PMF1-BGLAP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where PMF1-BGLAP RNA is repressed in tumor relative to normal tissue. In most cancer types PMF1-BGLAP is over-expressed in tumor, although a few such as KICH and READ show the opposite, repressed pattern.

KICH, LIHC, and BRCA are the cancer types where PMF1-BGLAP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PMF1-BGLAP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	III,IV	−0.970	<.001	10	view →
LIHC	Male	II,III,IV	+1.180	<.001	9	view →
BRCA	All	II,III,IV	+0.320	<.001	6	view →
HNSC	Male	III,IV	+0.395	.017	5	view →
CHOL	All	All	+1.102	<.001	4	view →
READ	Female	All	−0.641	.040	4	view →
KIRC	Male	IV	+0.334	.008	4	view →
PAAD	All	All	+0.507	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PMF1-BGLAP–KICH

Open the KICH breakdown →